Across TCGA cell cohorts, PPP3R1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,001 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP3R1-associated GO terms across cancer lineages are Regulation of cell cycle checkpoint, Regulation of hematopoietic stem cell differentiation, and Regulation of DNA damage checkpoint. Each is linked with PPP3R1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PPP3R1-to-partner and partner-to-PPP3R1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP3R1→partner) and Y-score (partner→PPP3R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of cell cycle checkpoint →	+0.123	+1.115	<.001	.002	3	13
BREAST	Regulation of hematopoietic stem cell differentiation →	+0.110	+0.631	<.001	<.001	3	13
KIDNEY	Regulation of DNA damage checkpoint →	+0.088	+1.088	<.001	<.001	3	13
STOMACH	Heterochromatin formation →	+0.074	+0.516	<.001	<.001	3	13
OVARY	Epigenetic regulation of gene expression →	+0.060	+0.663	.001	<.001	3	13
STOMACH	Negative regulation of gene expression, epigenetic →	+0.067	+0.469	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,001 associations by consensus.

Exploration

PPP3R1 survival (RNA) · tumor vs normal (RNA) · all PPP3R1 data types