PPP3CC

Across TCGA patient cohorts, PPP3CC RNA expression is significantly associated with the protein abundance of many other proteins, with 14,796 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP3CC-associated proteins across cancer lineages are SORBS3, PPP1R12C, and POLDIP2. Each is linked with PPP3CC in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP3CC-to-partner and partner-to-PPP3CC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP3CC versus SORBS3 in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP3CC→partner) and Y-score (partner→PPP3CC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SORBS3 →	+0.643	+0.952	<.001	<.001	3	8
LSCC	PPP1R12C →	+0.274	+0.550	<.001	<.001	3	7
OV	POLDIP2 →	-0.377	-0.949	<.001	<.001	3	6
COAD	KNOP1 →	-0.410	-0.446	.004	.005	3	6
UCEC	PDLIM2 →	+0.434	+0.717	<.001	<.001	3	6
GBM	CDKN2C →	+0.537	+0.340	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,796 associations by consensus.

PPP3CC vs SORBS3 — OV

Explore this scatter interactively →