PPP3CC

Across TCGA patient cohorts, PPP3CC protein abundance is significantly associated with the RNA expression of many other genes, with 15,936 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP3CC-associated genes across cancer lineages are CD28, GNG2, and ITM2A. Each is linked with PPP3CC in more than 6 cancer types. Because this analysis shows association rather than direction, both PPP3CC-to-partner and partner-to-PPP3CC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP3CC versus CD28 in LUAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP3CC→partner) and Y-score (partner→PPP3CC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CD28 →	+0.812	+0.246	<.001	<.001	3	7
OV	GNG2 →	+0.860	+0.555	<.001	<.001	3	7
HNSC	ITM2A →	+1.368	+0.266	<.001	<.001	3	7
GBM	PPP1R16B →	+1.458	+0.291	<.001	<.001	3	7
LSCC	GRAP2 →	+0.766	+0.387	<.001	<.001	3	6
HNSC	CD40LG →	+0.652	+0.294	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,936 associations by consensus.

PPP3CC vs CD28 — LUAD

Explore this scatter interactively →