PPP2R5D

Across TCGA patient cohorts, PPP2R5D protein abundance is significantly associated with the RNA expression of many other genes, with 13,043 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R5D-associated genes across cancer lineages are MEA1, CDC5L, and POLR1C. Each is linked with PPP2R5D in more than 6 cancer types. Because this analysis shows association rather than direction, both PPP2R5D-to-partner and partner-to-PPP2R5D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R5D versus MEA1 in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5D→partner) and Y-score (partner→PPP2R5D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MEA1 →	+0.621	+0.589	.005	.004	3	7
LSCC	CDC5L →	+0.635	+0.300	<.001	<.001	3	7
LSCC	POLR1C →	+0.664	+0.241	<.001	<.001	3	6
LSCC	TJAP1 →	+0.497	+0.219	<.001	<.001	3	6
GBM	CSF3R →	-0.884	-0.180	<.001	.002	3	5
LSCC	KLHDC3 →	+0.628	+0.282	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,043 associations by consensus.

PPP2R5D vs MEA1 — OV

Explore this scatter interactively →