PPP2R5CP

Across TCGA pan-cancer cohorts, PPP2R5CP RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PPP2R5CP data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PPP2R5CP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP2R5CP expression acts as an unfavorable survival marker, although some lineages such as SKCM and BLCA show a favorable association.

KIRC, UVM, and SKCM are the cancer types where PPP2R5CP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.542	0.699	<.001	158	view →
UVM	DFS	Median	All	0.566	0.870	<.001	122	view →
SKCM	OS	Tertile	All	0.843	0.707	<.001	68	view →
BLCA	OS	Tertile	II,III,IV	0.669	0.524	.004	63	view →
LIHC	OS	Median	All	0.433	0.603	.002	29	view →
THCA	DFS	Median	II,III,IV	0.848	0.454	.010	21	view →
READ	OS	Median	All	0.850	1.000	.002	19	view →
ESCA	DFS	Median	II,III,IV	0.269	0.490	.001	18	view →
KIRP	OS	Median	III,IV	0.241	0.628	.004	18	view →
LGG	DFS	Median	All	0.668	0.792	.001	15	view →
STAD	DFS	Median	All	0.496	0.613	.020	14	view →
LUSC	DFS	Quartile	All	0.562	0.829	.010	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PPP2R5CP–KIRC (DFS)

Open the KIRC breakdown →