PPP2R5B

Across TCGA patient cohorts, PPP2R5B RNA expression is significantly associated with the protein abundance of many other proteins, with 9,846 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R5B-associated proteins across cancer lineages are COQ8A, MRPS12, and RELA. Each is linked with PPP2R5B in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP2R5B-to-partner and partner-to-PPP2R5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R5B versus COQ8A in OV, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5B→partner) and Y-score (partner→PPP2R5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COQ8A →	-0.558	-0.714	.001	.001	3	5
OV	MRPS12 →	-0.427	-0.660	<.001	<.001	3	4
HNSC	RELA →	+0.173	+0.544	<.001	.003	3	4
GBM	BMPR2_S863 →	+0.338	+0.312	<.001	<.001	3	4
BRCA	ATL3 →	+0.416	+0.470	<.001	<.001	3	4
BRCA	MICAL2 →	+0.375	+0.493	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,846 associations by consensus.

PPP2R5B vs COQ8A — OV

Explore this scatter interactively →