PPP2R5B

Across TCGA patient cohorts, PPP2R5B protein abundance is significantly associated with the RNA expression of many other genes, with 9,420 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP2R5B-associated genes across cancer lineages are SLC38A5, NEB, and PRELID3B. Each is linked with PPP2R5B in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP2R5B-to-partner and partner-to-PPP2R5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R5B versus SLC38A5 in LSCC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5B→partner) and Y-score (partner→PPP2R5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLC38A5 →	+1.070	+0.185	<.001	<.001	3	3
CCRCC	NEB →	-0.795	-0.187	.002	<.001	3	3
LSCC	PRELID3B →	-0.548	-0.188	<.001	<.001	3	3
OV	RGS2 →	+1.164	+0.343	.008	.003	3	3
OV	GOT2 →	-0.793	-0.406	.002	.001	3	3
UCEC	MICAL2 →	+0.721	+0.215	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,420 associations by consensus.

PPP2R5B vs SLC38A5 — LSCC

Explore this scatter interactively →