PPP2R5B

Across TCGA cell cohorts, PPP2R5B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,596 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PPP2R5B-associated GO terms across cancer lineages are Regulation of intracellular transport, Positive regulation of autophagy, and Endosomal transport. Each is linked with PPP2R5B in more than 17 cancer types. Because this analysis shows association rather than direction, both PPP2R5B-to-partner and partner-to-PPP2R5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular transport grouped by PPP2R5B-low versus PPP2R5B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5B→partner) and Y-score (partner→PPP2R5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of intracellular transport →	+0.063	+1.100	<.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Positive regulation of autophagy →	+0.085	+1.800	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.051	+0.954	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.079	+1.671	<.001	<.001	3	16
SOFT_TISSUE	Autophagy of mitochondrion →	+0.090	+1.067	<.001	<.001	3	16
BLOOD_Myeloma	Macroautophagy →	+0.072	+1.420	<.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,596 associations by consensus.

Regulation of intracellular transport by PPP2R5B expression — PANCREAS

Explore this box plot interactively →