PPP2R5A

Across TCGA pan-cancer cohorts, PPP2R5A Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PPP2R5A data layer compared with 22 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PPP2R5A Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated PPP2R5A expression acts as an unfavorable survival marker, although some lineages such as UCEC and STAD show a favorable association.

UCEC, STAD, and PRAD are the cancer types where PPP2R5A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.966	0.628	.011	10	view →
STAD	DFS	Median	II,III,IV	1.000	0.335	.036	7	view →
PRAD	DFS	Median	All	0.617	0.886	.045	6	view →
SKCM	DFS	Median	All	0.275	0.614	.048	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PPP2R5A–UCEC (DFS)

Open the UCEC breakdown →