PPP2R5A

Across TCGA patient cohorts, PPP2R5A RNA expression is significantly associated with the protein abundance of many other proteins, with 19,797 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP2R5A-associated proteins across cancer lineages are GFPT2, SEC24A, and PRUNE1. Each is linked with PPP2R5A in more than 6 cancer types. Because this analysis shows association rather than direction, both PPP2R5A-to-partner and partner-to-PPP2R5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R5A versus GFPT2 in CCRCC, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5A→partner) and Y-score (partner→PPP2R5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GFPT2 →	-0.848	-0.365	.007	.005	2	7
CCRCC	SEC24A →	-0.281	-0.295	<.001	<.001	3	6
LUAD	PRUNE1 →	+0.313	+0.554	<.001	.001	3	6
CCRCC	NRBF2 →	-0.462	-0.366	<.001	<.001	3	6
GBM	TNFAIP8 →	-0.471	-0.373	<.001	<.001	3	6
UCEC	C1orf35 →	+0.455	+0.535	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,797 associations by consensus.

PPP2R5A vs GFPT2 — CCRCC

Explore this scatter interactively →