PPP2R5A

Across TCGA cell cohorts, PPP2R5A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,548 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PPP2R5A-associated GO terms across cancer lineages are Establishment of apical/basal cell polarity, Termination of RNA polymerase III transcription, and Regulation of extracellular matrix disassembly. Each is linked with PPP2R5A in more than 8 cancer types. Because this analysis shows association rather than direction, both PPP2R5A-to-partner and partner-to-PPP2R5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of apical/basal cell polarity grouped by PPP2R5A-low versus PPP2R5A-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5A→partner) and Y-score (partner→PPP2R5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Establishment of apical/basal cell polarity →	-0.216	-1.120	<.001	<.001	3	9
BONE	Termination of RNA polymerase III transcription →	-0.127	-1.134	.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of extracellular matrix disassembly →	-0.131	-0.470	.001	.004	3	8
BONE	Negative regulation of protein localization to plasma membrane →	+0.171	+1.045	<.001	<.001	3	8
BONE	Negative regulation of protein localization to membrane →	+0.128	+0.855	.002	.004	3	8
STOMACH	Mitochondrial protein catabolic process →	-0.154	-0.617	.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,548 associations by consensus.

Establishment of apical/basal cell polarity by PPP2R5A expression — SOFT_TISSUE

Explore this box plot interactively →