PPP2R3C

Across TCGA patient cohorts, PPP2R3C protein abundance is significantly associated with the RNA expression of many other genes, with 1,451 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R3C-associated genes across cancer lineages are ABRACL, GBP6, and VNN3. Each is linked with PPP2R3C in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP2R3C-to-partner and partner-to-PPP2R3C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R3C versus ABRACL in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R3C→partner) and Y-score (partner→PPP2R3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ABRACL →	+0.463	+0.341	.002	<.001	3	2
LSCC	GBP6 →	-1.574	-0.174	.002	.009	3	2
UCEC	VNN3 →	+1.433	+0.343	<.001	<.001	3	2
LSCC	ZNF812P →	-2.153	-0.273	<.001	<.001	3	2
LSCC	VENTXP6 →	-0.563	-0.177	.004	.008	3	2
BRCA	MAGOHB →	+0.542	+0.255	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,451 associations by consensus.

PPP2R3C vs ABRACL — GBM

Explore this scatter interactively →