PPP2R3C

Across TCGA cell cohorts, PPP2R3C RNA expression is significantly associated with the go_rna of many other GO terms, with 2,341 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PPP2R3C-associated GO terms across cancer lineages are Positive regulation of B cell differentiation, Protein localization to condensed chromosome, and Meiotic metaphase chromosome alignment. Each is linked with PPP2R3C in more than 11 cancer types. Because this analysis shows association rather than direction, both PPP2R3C-to-partner and partner-to-PPP2R3C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of B cell differentiation grouped by PPP2R3C-low versus PPP2R3C-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R3C→partner) and Y-score (partner→PPP2R3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of B cell differentiation →	+0.237	+0.921	<.001	.003	3	12
LUNG_NSCLC_LUSC	Protein localization to condensed chromosome →	+0.177	+1.247	.002	.001	3	12
KIDNEY	Meiotic metaphase chromosome alignment →	+0.098	+0.836	<.001	.001	3	12
URINARY_TRACT	Actin filament fragmentation →	+0.124	+1.222	<.001	.001	2	12
LUNG_NSCLC_LUSC	Protein localization to kinetochore →	+0.158	+0.978	.003	.007	3	11
BREAST	Interstrand cross-link repair →	+0.074	+0.809	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,341 associations by consensus.

Positive regulation of B cell differentiation by PPP2R3C expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →