PPP2R3C

Across TCGA cell cohorts, PPP2R3C mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PPP2R3C-associated genes across cancer lineages are COX4I2. Each is linked with PPP2R3C in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP2R3C-to-partner and partner-to-PPP2R3C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX4I2 grouped by PPP2R3C-low versus PPP2R3C-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R3C→partner) and Y-score (partner→PPP2R3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	COX4I2 →	+0.098	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

COX4I2 by PPP2R3C expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →