PPP2R3A

Across TCGA pan-cancer cohorts, PPP2R3A mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PPP2R3A data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PPP2R3A mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PPP2R3A expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD, CCRCC, and GBM are the cancer types where PPP2R3A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.870	0.351	<.001	24	view →
CCRCC	DFS	Tertile	III,IV	0.517	0.918	.011	11	view →
GBM	OS	Quartile	All	0.621	0.959	.005	10	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PPP2R3A–LUAD (OS)

Open the LUAD breakdown →