PPP2R3A

Across TCGA patient cohorts, PPP2R3A RNA expression is significantly associated with the protein abundance of many other proteins, with 15,846 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP2R3A-associated proteins across cancer lineages are PPP2R3A_S505, PPP2R3A_S562, and PPP2R3A_S692. Each is linked with PPP2R3A in more than 6 cancer types. Because this analysis shows association rather than direction, both PPP2R3A-to-partner and partner-to-PPP2R3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R3A versus PPP2R3A_S505 in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R3A→partner) and Y-score (partner→PPP2R3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPP2R3A_S505 →	+0.920	+1.278	<.001	<.001	3	6
BRCA	PPP2R3A_S562 →	+1.278	+1.278	.002	<.001	3	6
HNSC	PPP2R3A_S692 →	+0.668	+0.681	<.001	.001	2	7
LSCC	GSK3B →	+0.456	+1.040	<.001	<.001	3	4
CCRCC	SNX4 →	+0.349	+1.000	<.001	<.001	3	4
LUAD	ATP2A3 →	-0.410	-0.849	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,846 associations by consensus.

PPP2R3A vs PPP2R3A_S505 — LSCC

Explore this scatter interactively →