PPP2R3A

Across TCGA patient cohorts, PPP2R3A protein abundance is significantly associated with the RNA expression of many other genes, with 10,088 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PPP2R3A-associated genes across cancer lineages are NCEH1, MBD4, and RNF181. Each is linked with PPP2R3A in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP2R3A-to-partner and partner-to-PPP2R3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R3A versus NCEH1 in CCRCC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R3A→partner) and Y-score (partner→PPP2R3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NCEH1 →	+0.850	+0.301	<.001	.002	3	3
LUAD	MBD4 →	+0.314	+0.393	.004	<.001	3	3
CCRCC	RNF181 →	+0.360	+0.290	<.001	<.001	3	3
LUAD	ZDHHC9 →	+0.758	+0.504	<.001	<.001	3	3
CCRCC	ARHGEF34P →	+0.531	+0.296	.003	.002	3	3
LUAD	RNF19A →	+0.726	+0.408	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,088 associations by consensus.

PPP2R3A vs NCEH1 — CCRCC

Explore this scatter interactively →