PPP2R3A

Across TCGA cell cohorts, PPP2R3A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,300 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPP2R3A-associated GO terms across cancer lineages are Response to hydrostatic pressure, Endosomal transport, and Process utilizing autophagic mechanism. Each is linked with PPP2R3A in more than 13 cancer types. Because this analysis shows association rather than direction, both PPP2R3A-to-partner and partner-to-PPP2R3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to hydrostatic pressure grouped by PPP2R3A-low versus PPP2R3A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R3A→partner) and Y-score (partner→PPP2R3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to hydrostatic pressure →	+0.178	+1.247	<.001	<.001	3	14
STOMACH	Endosomal transport →	+0.059	+1.473	.001	.001	3	13
STOMACH	Process utilizing autophagic mechanism →	+0.062	+1.565	<.001	<.001	3	13
STOMACH	Autophagy →	+0.062	+1.565	<.001	<.001	3	13
BONE	Regulation of cell-substrate junction assembly →	+0.165	+1.511	<.001	<.001	3	13
BONE	Regulation of focal adhesion assembly →	+0.165	+1.511	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,300 associations by consensus.

Response to hydrostatic pressure by PPP2R3A expression — BONE

Explore this box plot interactively →