PPP2R2B-IT1

Across TCGA pan-cancer cohorts, PPP2R2B-IT1 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated PPP2R2B-IT1 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher PPP2R2B-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPP2R2B-IT1 expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

PAAD, THYM, and OV are the cancer types where PPP2R2B-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Tertile	All	0.037	0.641	<.001	72	view →
THYM	DFS	Tertile	III,IV	0.205	0.774	.007	45	view →
OV	OS	Tertile	IV	0.028	0.759	.002	36	view →
CESC	DFS	Tertile	II,III,IV	0.140	0.785	<.001	36	view →
CHOL	OS	Tertile	All	0.155	0.725	.029	9	view →
PCPG	OS	Tertile	All	0.539	0.953	.041	9	view →
LGG	OS	Quartile	All	0.946	0.884	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

PPP2R2B-IT1–PAAD (OS)

Open the PAAD breakdown →