PPP2R2A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PPP2R2A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,398 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R2A-associated proteins across cancer lineages are PCM1, XPO7, and PPP2CB. Each is linked with PPP2R2A in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP2R2A-to-partner and partner-to-PPP2R2A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R2A→partner) and Y-score (partner→PPP2R2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAPCM1 →+0.516+0.639<.001<.00138
HNSCXPO7 →+0.325+0.558<.001<.00138
OVPPP2CB →+0.508+0.663.001<.00138
BRCACHMP7 →+0.329+0.730<.001<.00138
OVCCAR2 →+0.401+0.663<.001<.00138
OVPPP2R1A →+0.210+0.549<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,398 associations by consensus.

Exploration