Across TCGA patient cohorts, PPP2R2A protein abundance is significantly associated with the RNA expression of many other genes, with 9,120 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPP2R2A-associated genes across cancer lineages are PPP2CB, DCTN6, and ELP3. Each is linked with PPP2R2A in more than 8 cancer types. Because this analysis shows association rather than direction, both PPP2R2A-to-partner and partner-to-PPP2R2A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R2A→partner) and Y-score (partner→PPP2R2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPP2CB →	+0.650	+0.416	<.001	<.001	3	9
BRCA	DCTN6 →	+0.743	+0.611	<.001	<.001	3	8
UCEC	ELP3 →	+1.060	+0.360	.003	<.001	2	9
BRCA	VPS37A →	+0.683	+0.475	<.001	<.001	3	8
COAD	CNOT7 →	+0.606	+0.356	<.001	<.001	3	8
BRCA	PCM1 →	+0.972	+0.569	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,120 associations by consensus.

Exploration

PPP2R2A survival (RNA) · tumor vs normal (RNA) · all PPP2R2A data types