Across TCGA cell cohorts, PPP2R2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,869 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPP2R2A-associated GO terms across cancer lineages are Regulation of regulatory ncRNA-mediated heterochromatin formation, snRNA metabolic process, and Negative regulation of sister chromatid cohesion. Each is linked with PPP2R2A in more than 12 cancer types. Because this analysis shows association rather than direction, both PPP2R2A-to-partner and partner-to-PPP2R2A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R2A→partner) and Y-score (partner→PPP2R2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.157	+1.149	<.001	<.001	3	13
BONE	snRNA metabolic process →	+0.068	+1.011	.001	<.001	3	13
BLOOD_Myeloma	Negative regulation of sister chromatid cohesion →	+0.139	+1.347	.003	.001	3	13
LIVER	Negative regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.157	+1.149	<.001	<.001	3	13
BONE	Negative regulation of heterochromatin organization →	+0.121	+0.995	<.001	<.001	3	12
SKIN	Positive regulation of telomere capping →	+0.141	+0.761	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,869 associations by consensus.

Exploration

PPP2R2A survival (RNA) · tumor vs normal (RNA) · all PPP2R2A data types