Across TCGA pan-cancer cohorts, PPP1R3G Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PPP1R3G data layer compared with 21 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PPP1R3G Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PPP1R3G expression acts as an unfavorable survival marker.

UCEC, MESO, and COAD are the cancer types where PPP1R3G Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.231	0.768	.010	24	view →
MESO	DFS	Median	III,IV	0.082	0.414	.007	18	view →
COAD	DFS	Median	All	0.235	0.797	<.001	11	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: PPP1R3G tumor-vs-normal RNA expression · all PPP1R3G data types