Across TCGA pan-cancer cohorts, PPP1R3G mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PPP1R3G data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PPP1R3G mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R3G expression acts as an unfavorable survival marker.

LUAD, PDAC, and HNSC are the cancer types where PPP1R3G mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.858	0.999	.010	16	view →
PDAC	DFS	Tertile	All	0.312	0.450	.031	6	view →
HNSC	OS	Median	All	0.484	1.000	.038	6	view →
GBM	OS	Quartile	All	0.348	0.621	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: PPP1R3G tumor-vs-normal RNA expression · all PPP1R3G data types