PPP1R3E

Across TCGA pan-cancer cohorts, PPP1R3E mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PPP1R3E data layer compared with 22 for mass-spec protein.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PPP1R3E mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PPP1R3E expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC and HNSC are the cancer types where PPP1R3E mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.934	0.488	.001	39	view →
HNSC	DFS	Tertile	III,IV	0.914	0.551	.014	19	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PPP1R3E–CCRCC (DFS)

Open the CCRCC breakdown →