PPP1R3B

Across TCGA pan-cancer cohorts, PPP1R3B mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PPP1R3B data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PPP1R3B mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R3B expression acts as an unfavorable survival marker.

HNSC, LUAD, and PDAC are the cancer types where PPP1R3B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.205	0.860	.010	10	view →
LUAD	OS	Median	All	0.586	0.846	.020	6	view →
PDAC	DFS	Median	II,III,IV	0.241	0.428	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PPP1R3B–HNSC (DFS)

Open the HNSC breakdown →