PPP1R3B

Across TCGA cell cohorts, PPP1R3B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,672 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPP1R3B-associated GO terms across cancer lineages are Lysosomal transport, Regulation of regulatory ncRNA-mediated heterochromatin formation, and Vacuolar transport. Each is linked with PPP1R3B in more than 10 cancer types. Because this analysis shows association rather than direction, both PPP1R3B-to-partner and partner-to-PPP1R3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosomal transport grouped by PPP1R3B-low versus PPP1R3B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3B→partner) and Y-score (partner→PPP1R3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Lysosomal transport →	+0.067	+1.756	<.001	<.001	3	11
URINARY_TRACT	Regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.133	+1.448	<.001	<.001	3	10
URINARY_TRACT	Vacuolar transport →	+0.059	+1.688	.003	<.001	3	10
URINARY_TRACT	Negative regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.133	+1.448	<.001	<.001	3	10
KIDNEY	Protein localization to lysosome →	+0.062	+1.189	.009	.005	3	10
PANCREAS	Establishment of protein localization to vacuole →	+0.044	+0.624	.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,672 associations by consensus.

Lysosomal transport by PPP1R3B expression — URINARY_TRACT

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