PPP1R3A

Across TCGA pan-cancer cohorts, PPP1R3A mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PPP1R3A data layer compared with 14 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PPP1R3A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R3A expression acts as an unfavorable survival marker.

HNSC and LSCC are the cancer types where PPP1R3A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	II,III,IV	0.906	0.987	.012	8	view →
LSCC	DFS	Median	All	0.133	1.000	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PPP1R3A–HNSC (DFS)

Open the HNSC breakdown →