PPP1R37

Across TCGA pan-cancer cohorts, PPP1R37 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PPP1R37 data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PPP1R37 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R37 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

CCRCC, PDAC, and GBM are the cancer types where PPP1R37 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	II,III,IV	0.468	0.899	<.001	25	view →
PDAC	OS	Tertile	IV	0.425	0.962	.024	6	view →
GBM	DFS	Median	All	0.770	0.666	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PPP1R37–CCRCC (DFS)

Open the CCRCC breakdown →