PPP1R37

Across TCGA patient cohorts, PPP1R37 protein abundance is significantly associated with the RNA expression of many other genes, with 9,657 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPP1R37-associated genes across cancer lineages are IL11RA, NECTIN2, and CLPTM1. Each is linked with PPP1R37 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP1R37-to-partner and partner-to-PPP1R37 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R37 versus IL11RA in HNSC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R37→partner) and Y-score (partner→PPP1R37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IL11RA →	-0.663	-0.209	<.001	<.001	3	5
PDAC	NECTIN2 →	+0.584	+0.281	<.001	<.001	3	5
LUAD	CLPTM1 →	+0.425	+0.203	.002	.001	3	4
LSCC	CCNB1IP1 →	-0.668	-0.241	<.001	<.001	3	3
BRCA	TNFRSF8 →	-0.513	-0.394	<.001	<.001	3	3
OV	ECSIT →	-0.739	-0.343	.002	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,657 associations by consensus.

PPP1R37 vs IL11RA — HNSC

Explore this scatter interactively →