PPP1R37

Across TCGA patient cohorts, PPP1R37 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R37-associated genes across cancer lineages are RNA5SP124, RNU6-1085P, and SNORD31B. Each is linked with PPP1R37 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R37-to-partner and partner-to-PPP1R37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP124 grouped by PPP1R37-low versus PPP1R37-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R37→partner) and Y-score (partner→PPP1R37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP124 →	+0.618	+4.581	.001	.001	3	1
UCEC	RNU6-1085P →	+0.602	+4.184	<.001	.003	3	1
UCEC	SNORD31B →	+0.499	+4.997	<.001	.003	3	1
UCEC	RNU6-784P →	+0.528	+5.935	<.001	<.001	3	1
UCEC	RNU6-1026P →	+0.427	+4.352	.001	.008	3	1
UCEC	SNORD90 →	+0.495	+3.840	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

RNA5SP124 by PPP1R37 expression — UCEC

Explore this box plot interactively →