PPP1R37

Across TCGA cell cohorts, PPP1R37 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,884 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R37-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Negative regulation of protein-containing complex assembly, and Positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Each is linked with PPP1R37 in more than 16 cancer types. Because this analysis shows association rather than direction, both PPP1R37-to-partner and partner-to-PPP1R37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by PPP1R37-low versus PPP1R37-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R37→partner) and Y-score (partner→PPP1R37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of calcium ion export across plasma membrane →	+0.086	+1.226	.006	.002	3	17
OESOPHAGUS	Negative regulation of protein-containing complex assembly →	+0.114	+1.228	<.001	.001	3	14
BONE	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.084	+0.878	<.001	<.001	3	14
STOMACH	Endosomal transport →	+0.065	+0.973	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of proteasomal protein catabolic process →	+0.062	+0.794	<.001	<.001	3	14
LIVER	Cytokinetic process →	+0.093	+0.745	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,884 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by PPP1R37 expression — OESOPHAGUS

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