PPP1R37

Across TCGA cell cohorts, PPP1R37 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP1R37-associated genes across cancer lineages are MMP27, FSHR, and KCNK18. Each is linked with PPP1R37 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R37-to-partner and partner-to-PPP1R37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP27 grouped by PPP1R37-low versus PPP1R37-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R37→partner) and Y-score (partner→PPP1R37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MMP27 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	FSHR →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	KCNK18 →	+0.020	+4.906	<.001	.006	3	1
OESOPHAGUS	LCE1F →	+0.330	+4.906	<.001	.006	3	1
OESOPHAGUS	CCDC195 →	+0.043	+4.906	<.001	.006	3	1
PANCREAS	RS1 →	+0.006	+4.011	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

MMP27 by PPP1R37 expression — OESOPHAGUS

Explore this box plot interactively →