PPP1R2P5

Across TCGA patient cohorts, PPP1R2P5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,310 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPP1R2P5-associated GO terms across cancer lineages are Macromolecule methylation, Regulation of oxidative stress-induced intrinsic apoptotic signaling pathway, and Protein monoubiquitination. Each is linked with PPP1R2P5 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP1R2P5-to-partner and partner-to-PPP1R2P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule methylation grouped by PPP1R2P5-low versus PPP1R2P5-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R2P5→partner) and Y-score (partner→PPP1R2P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Macromolecule methylation →	+0.046	+0.013	<.001	.007	3	5
SARC	Regulation of oxidative stress-induced intrinsic apoptotic signaling pathway →	+0.039	+0.032	<.001	<.001	3	4
STAD	Protein monoubiquitination →	+0.026	+0.050	.005	.003	3	4
LUSC	Nucleoside phosphate biosynthetic process →	+0.047	+0.033	<.001	<.001	3	4
STAD	Negative regulation of Rho protein signal transduction →	+0.036	+0.045	<.001	.004	3	4
STAD	Regulation of generation of precursor metabolites and energy →	+0.031	+0.050	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,310 associations by consensus.

Macromolecule methylation by PPP1R2P5 expression — LUSC

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