PPP1R2P4

Across TCGA patient cohorts, PPP1R2P4 mutation is significantly associated with the RNA expression of many other genes, with 148 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R2P4-associated genes across cancer lineages are RN7SKP46, LINC01066, and RNA5SP258. Each is linked with PPP1R2P4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R2P4-to-partner and partner-to-PPP1R2P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP46 grouped by PPP1R2P4-low versus PPP1R2P4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R2P4→partner) and Y-score (partner→PPP1R2P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP46 →	+0.106	+4.566	<.001	.003	3	2
SKCM	LINC01066 →	+0.256	+4.208	<.001	.003	3	2
BLCA	RNA5SP258 →	+0.388	+7.640	<.001	.009	3	1
BLCA	RNU6-756P →	+0.333	+7.640	<.001	.009	3	1
BLCA	MIR592 →	+0.418	+7.640	<.001	.009	3	1
SKCM	CTSLP2 →	+0.364	+4.177	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 148 associations by consensus.

RN7SKP46 by PPP1R2P4 expression — UCEC

Explore this box plot interactively →