PPP1R2P2

Across TCGA pan-cancer cohorts, PPP1R2P2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated PPP1R2P2 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PPP1R2P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPP1R2P2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and TGCT show a favorable association.

UVM, COAD, and CESC are the cancer types where PPP1R2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.136	0.919	<.001	51	view →
COAD	DFS	Tertile	IV	0.118	0.532	.004	45	view →
CESC	DFS	Tertile	II,III,IV	0.105	0.514	.014	42	view →
SKCM	DFS	Tertile	IV	0.042	0.471	.003	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
LIHC	OS	Tertile	All	0.654	0.817	.002	33	view →
LUAD	OS	Tertile	II,III,IV	0.412	0.139	.006	31	view →
KIRP	OS	Tertile	II,III,IV	0.590	0.849	.014	24	view →
CHOL	DFS	Quartile	All	0.146	0.590	<.001	21	view →
HNSC	OS	Tertile	IV	0.233	0.541	.014	18	view →
KIRC	DFS	Tertile	All	0.506	0.680	.013	15	view →
BLCA	DFS	Tertile	III,IV	0.376	0.591	.011	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

PPP1R2P2–UVM (OS)

Open the UVM breakdown →