PPP1R2P1

Across TCGA patient cohorts, PPP1R2P1 mutation is significantly associated with the RNA expression of many other genes, with 77 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R2P1-associated genes across cancer lineages are SMIM28, RN7SL592P, and MIR3612. Each is linked with PPP1R2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R2P1-to-partner and partner-to-PPP1R2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM28 grouped by PPP1R2P1-low versus PPP1R2P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R2P1→partner) and Y-score (partner→PPP1R2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SMIM28 →	+0.806	+2.955	<.001	.007	3	1
UCEC	RN7SL592P →	+0.218	+2.860	.002	.004	3	1
UCEC	MIR3612 →	+0.346	+3.186	.003	.008	3	1
UCEC	RN7SL118P →	+0.396	+2.834	.004	.009	3	1
UCEC	ATP5MGP6 →	+0.406	+3.097	<.001	.004	3	1
UCEC	H3Y2 →	+0.589	+2.563	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

SMIM28 by PPP1R2P1 expression — UCEC

Explore this box plot interactively →