PPP1R2B

Across TCGA pan-cancer cohorts, PPP1R2B RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated PPP1R2B data layer compared with 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PPP1R2B RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PPP1R2B expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

LUAD, MESO, and OV are the cancer types where PPP1R2B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.429	0.239	<.001	29	view →
MESO	DFS	Tertile	All	0.297	0.686	.012	27	view →
OV	DFS	Tertile	All	0.124	0.208	.013	18	view →
SKCM	OS	Tertile	All	0.481	0.186	.005	16	view →
READ	DFS	Tertile	III,IV	0.505	0.194	.008	9	view →
LUSC	DFS	Quartile	All	0.494	0.293	.006	9	view →
KICH	DFS	Tertile	III,IV	0.450	1.000	.011	7	view →
THCA	DFS	Median	III,IV	0.925	0.789	.021	7	view →
DLBC	DFS	Tertile	All	0.481	1.000	.037	7	view →
HNSC	OS	Tertile	All	0.589	0.737	.012	6	view →
BRCA	DFS	Median	IV	0.850	0.566	.027	4	view →
BLCA	DFS	Tertile	All	0.676	0.536	.019	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

PPP1R2B–LUAD (DFS)

Open the LUAD breakdown →