PPP1R27

Across TCGA patient cohorts, PPP1R27 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,902 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1R27-associated proteins across cancer lineages are KPNA2, DDX39A, and DHX33. Each is linked with PPP1R27 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP1R27-to-partner and partner-to-PPP1R27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R27 versus KPNA2 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R27→partner) and Y-score (partner→PPP1R27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KPNA2 →	+0.539	+0.268	.003	.004	3	5
BRCA	DDX39A →	+0.443	+0.321	.001	<.001	3	5
LSCC	DHX33 →	+0.311	+0.433	<.001	<.001	3	5
BRCA	RFC1 →	+0.343	+0.253	<.001	.005	3	4
LSCC	HEATR1 →	+0.355	+0.572	<.001	<.001	3	4
LSCC	KDM3A →	+0.478	+0.586	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,902 associations by consensus.

PPP1R27 vs KPNA2 — BRCA

Explore this scatter interactively →