PPP1R27

Across TCGA patient cohorts, PPP1R27 protein abundance is significantly associated with the RNA expression of many other genes, with 515 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PPP1R27-associated genes across cancer lineages are MYLK2, TNNC2, and MYOM1. Each is linked with PPP1R27 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R27-to-partner and partner-to-PPP1R27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R27 versus MYLK2 in HNSC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R27→partner) and Y-score (partner→PPP1R27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYLK2 →	+1.365	+0.842	<.001	.001	3	1
HNSC	TNNC2 →	+2.670	+0.895	.006	.008	3	1
HNSC	MYOM1 →	+1.375	+0.910	.009	.004	3	1
HNSC	ATP1B4 →	+1.449	+1.019	<.001	<.001	3	1
HNSC	CKM →	+3.705	+0.876	<.001	<.001	3	1
HNSC	DMPK →	+1.225	+1.276	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 515 associations by consensus.

PPP1R27 vs MYLK2 — HNSC

Explore this scatter interactively →