Across TCGA pan-cancer cohorts, PPP1R26P2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of PPP1R26P2’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where PPP1R26P2 RNA is repressed in tumor relative to normal tissue. In most cancer types PPP1R26P2 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA are the cancer types where PPP1R26P2 tumor–normal differential expression is most reproducible.