Across TCGA pan-cancer cohorts, PPP1R26 mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PPP1R26’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where PPP1R26 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types PPP1R26 is over-expressed in tumor, although a few such as PDAC show the opposite, repressed pattern.

PDAC and LUAD are the cancer types where PPP1R26 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPP1R26 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PDAC	Female	All	−1.930	.019	4	view →
LUAD	All	All	+1.512	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: PPP1R26 RNA expression & survival · all PPP1R26 data types