Across TCGA patient cohorts, PPP1R26 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R26-associated genes across cancer lineages are PCNA, Caspase-7-cleavedD198, and eEF2. Each is linked with PPP1R26 in more than 3 cancer types. Because this analysis shows association rather than direction, both PPP1R26-to-partner and partner-to-PPP1R26 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R26→partner) and Y-score (partner→PPP1R26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.194	+1.432	.002	.005	3	4
COAD	Caspase-7-cleavedD198 →	+1.097	+2.593	<.001	.006	3	3
SKCM	eEF2 →	+0.406	+2.584	.007	.011	3	3
STAD	VHL →	+0.986	+3.321	.007	.010	3	2
STAD	Claudin-7 →	+0.682	+3.321	.027	.010	3	2
UCEC	Cyclin-B1 →	+0.507	+1.637	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration

PPP1R26 survival (RNA) · tumor vs normal (RNA) · all PPP1R26 data types