PPP1R2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PPP1R2 mutation is significantly associated with the RNA expression of many other genes, with 3,476 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R2-associated genes across cancer lineages are GOLGA2P3Y, LINC02479, and FAM32DP. Each is linked with PPP1R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R2-to-partner and partner-to-PPP1R2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R2→partner) and Y-score (partner→PPP1R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCGOLGA2P3Y →+0.020+4.655<.001.00732
SKCMLINC02479 →+0.049+7.816<.001.00832
SKCMFAM32DP →+0.094+7.816<.001.00832
UCECRNU6-1292P →+0.204+2.868<.001.00932
UCECLINC00534 →+0.131+1.645.001.00932
COADPIGPP2 →+0.144+5.917<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,476 associations by consensus.

Exploration