PPP1R2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PPP1R2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,111 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PPP1R2-associated GO terms across cancer lineages are Protein modification by small protein removal, Positive regulation of post-translational protein modification, and Positive regulation of protein modification by small protein conjugation or removal. Each is linked with PPP1R2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PPP1R2-to-partner and partner-to-PPP1R2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R2→partner) and Y-score (partner→PPP1R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASProtein modification by small protein removal →+0.038+0.635.002.00839
OVARYPositive regulation of post-translational protein modification →+0.068+0.814<.001.00239
BONEPositive regulation of protein modification by small protein conjugation or removal →+0.071+0.709.002<.00139
BREASTMaintenance of centrosome location →+0.088+0.697<.001<.00139
SOFT_TISSUEProtein polyubiquitination →+0.045+0.630<.001<.00139
BLOOD_MyelomaMacroautophagy →+0.056+0.850<.001.00439
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,111 associations by consensus.

Exploration