PPP1R18

Across TCGA pan-cancer cohorts, PPP1R18 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PPP1R18 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PPP1R18 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R18 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

COAD, GBM, and LUAD are the cancer types where PPP1R18 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.880	1.000	.020	24	view →
GBM	DFS	Quartile	All	0.217	0.496	.005	21	view →
LUAD	DFS	Median	All	0.736	0.485	.030	2	view →
HNSC	OS	Tertile	III,IV	0.543	0.773	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PPP1R18–COAD (DFS)

Open the COAD breakdown →