PPP1R18

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PPP1R18 protein abundance is significantly associated with the RNA expression of many other genes, with 20,744 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1R18-associated genes across cancer lineages are CYTH4, TLR8, and IL21R. Each is linked with PPP1R18 in more than 8 cancer types. Because this analysis shows association rather than direction, both PPP1R18-to-partner and partner-to-PPP1R18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R18 versus CYTH4 in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R18→partner) and Y-score (partner→PPP1R18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCYTH4 →+0.951+0.480<.001<.00139
HNSCTLR8 →+0.990+0.429<.001<.00139
UCECIL21R →+1.075+0.649<.001<.00139
OVLILRB1 →+1.138+0.559<.001<.00139
UCECCD33 →+0.764+0.566<.001<.00139
COADMS4A4A →+1.053+0.398<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,744 associations by consensus.

PPP1R18 vs CYTH4 — UCEC

Per-sample scatter of PPP1R18 vs CYTH4 in UCEC (Pearson r = 0.47).

Explore this scatter interactively →

Exploration