PPP1R18

Across TCGA cell cohorts, PPP1R18 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,108 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPP1R18-associated GO terms across cancer lineages are Dentinogenesis, Positive regulation of cell-substrate adhesion, and Positive regulation of supramolecular fiber organization. Each is linked with PPP1R18 in more than 15 cancer types. Because this analysis shows association rather than direction, both PPP1R18-to-partner and partner-to-PPP1R18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dentinogenesis grouped by PPP1R18-low versus PPP1R18-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R18→partner) and Y-score (partner→PPP1R18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Dentinogenesis →	+2.085	+1.226	<.001	<.001	3	16
BONE	Positive regulation of cell-substrate adhesion →	+0.141	+0.975	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Positive regulation of supramolecular fiber organization →	+0.136	+2.052	.001	.003	3	14
BREAST	Urokinase plasminogen activator signaling pathway →	+1.255	+1.383	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Coagulation →	+0.147	+2.201	.007	.001	3	14
BONE	Blood coagulation →	+0.116	+1.141	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,108 associations by consensus.

Dentinogenesis by PPP1R18 expression — BONE

Explore this box plot interactively →