PPP1R17

Across TCGA cell cohorts, PPP1R17 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP1R17-associated genes across cancer lineages are COX6A2, TBC1D21, and CCER1. Each is linked with PPP1R17 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R17-to-partner and partner-to-PPP1R17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX6A2 grouped by PPP1R17-low versus PPP1R17-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R17→partner) and Y-score (partner→PPP1R17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	COX6A2 →	+0.082	+4.437	<.001	.004	3	1
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	CCER1 →	+0.013	+4.562	<.001	<.001	3	1
LARGE_INTESTINE	TECRL →	+0.017	+4.562	<.001	<.001	3	1
LARGE_INTESTINE	OR5V1 →	+0.008	+4.437	<.001	.004	3	1
LARGE_INTESTINE	OR6Q1 →	+0.018	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

COX6A2 by PPP1R17 expression — LARGE_INTESTINE

Explore this box plot interactively →