Across TCGA patient cohorts, PPP1R14C RNA expression is significantly associated with the protein abundance of many other proteins, with 13,453 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPP1R14C-associated proteins across cancer lineages are PPP1R14C_S158, PPP1R14C_S25, and PPP1R14C_S33. Each is linked with PPP1R14C in more than 8 cancer types. Because this analysis shows association rather than direction, both PPP1R14C-to-partner and partner-to-PPP1R14C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R14C→partner) and Y-score (partner→PPP1R14C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPP1R14C_S158 →	+1.823	+1.910	<.001	<.001	3	9
OV	PPP1R14C_S25 →	+1.712	+2.473	.004	.002	2	7
OV	PPP1R14C_S33 →	+3.147	+2.523	<.001	<.001	3	6
BRCA	VSNL1 →	+0.916	+1.345	<.001	.007	3	5
BRCA	NAXE →	-0.390	-1.724	<.001	<.001	3	4
HNSC	SQLE →	+0.528	+1.084	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,453 associations by consensus.

Exploration

PPP1R14C survival (RNA) · tumor vs normal (RNA) · all PPP1R14C data types